Creating a New Annotation Property in Protege

1. Go to the Annotation properties tab.

2. Add a new property using the “+” (similar to adding a class)

3. Name the annotation property
   The IRI for annotation properties should do not have numerical ID.
   The convention for Annotation Property IRI in Mondo is : http://purl.obolibrary.org/obo/mondo#new_property where

   • mondo = ontology where the property is created

   • new_property = name of the annotation property, preceded by #

In order to create this IRI, manually add the IRI when creating the annotation property, as shown here:

1. Add annotations to this new property.
   This can be done by adding “Annotations” as would be done for any other class. Annotation required:
2. rdfs:label
3. is_metadata_tag with ‘true’ (added as literal)

Note: - "is_metadata_tag" MUST be added when adding a new annotation property in obo, in order to obo to recognize the new annotation property.
- Even though no other annotations are required for annotation properties, it is a idea to add a comment or other useful informationt hat would allow someone to re-use the annotation property. Minimal required information is proposed here .